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Tacgrafs is a strong immunosuppressive drug frequently provided to individuals who have had organ transplantation to avoid organ rejection, such as kidney, liver, or heart transplants. It is particularly effective in reducing the activity of the immune system by inhibiting the production of certain immune cells, which helps prevent the immune system from attacking and damaging the transplanted organ.

Manufacturer

CCL Pharmaceuticals (Pvt) Ltd

Country of Origin

Pakistan

Pack Form

Pack of 30 capsules

Product Form

capsules

Product Type

Medicine



Follow your healthcare provider's instructions regarding dosage and administration, and take the medication exactly as prescribed. Do not change the dose without consulting your doctor.

Tacgraf is usually taken orally, typically twice daily, and should be taken consistently with or without food.


There are some potential side effects of Tacgraf 0.5mg capsules. Keep in mind that not everyone will have these side effects, and their intensity may vary:

  • Common Side Effects:
    • Headache
    • Nausea
    • Diarrhea
    • Upset stomach
    • Tremors or shaking
    • Increased blood pressure
    • Increased risk of infection
    • Swelling in the hands or feet

Note: It's crucial to note that this medication requires close monitoring by a healthcare professional. Dosage adjustments might be necessary to balance its benefits and risks, and any signs of adverse effects should be reported promptly. As individual responses can vary, patients should carefully follow their doctor's instructions and attend all recommended check-ups to ensure the medication's safe and effective use. 


Some key drug interaction points for Tacgraf Capsules (0.5mg, 30's):

  • CYP3A4 Inhibitors: Concurrent use of strong CYP3A4 inhibitors (e.g., ketoconazole) with Tacrolimus can increase tacrolimus levels, potentially leading to toxicity.
  • CYP3A4 Inducers: Strong CYP3A4 inducers (e.g., rifampin) may decrease tacrolimus levels, reducing its efficacy; dosage adjustments might be necessary.
  • Grapefruit Juice: Avoid grapefruit juice, as it can inhibit CYP3A4 enzymes and increase tacrolimus levels.
  • Nephrotoxic Drugs: Combining nephrotoxic drugs (e.g., NSAIDs) with Tacrolimus can increase the risk of kidney damage.
  • Live Vaccines: Tacrolimus can impair the immune response; avoid live vaccines during treatment.

1.What is a Tacgraf 0.5mg capsule used for? 

Tacgraf 0.5mg capsules primarily prevent the body's immune system from attacking and rejecting organ transplants. It is commonly prescribed for patients who have received kidney, liver, or heart transplants.

2.How does Tacgraf work? 

Tacgraf is an immunosuppressive medication. It works by suppressing the activity of certain immune cells, particularly T-cells, which play a key role in the body's immune response. Tacgraf helps prevent the immune system from attacking and rejecting the transplanted organ by dampening the immune response.

3.How should I take Tacgraf capsules? 

Follow your doctor's instructions carefully. Tacgraf is usually taken orally, with or without food. It's important to take the medication simultaneously each day to maintain a consistent level in your body. Do not crush or chew the capsules unless instructed by your doctor.

4.What are the possible side effects of Tacgraf? 

Common side effects may include headache, tremors, increased blood pressure, stomach upset, diarrhea, and changes in kidney function. Serious side effects can include infections, skin cancer, high potassium levels, and nerve damage. It's important to discuss any side effects with your doctor.

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